Urticaria is a condition characterized by erythematous, oedematous, itchy eruptions covering the skin and mucous membranes. A 55-year-old female diagnosed with Urticaria presented with complaints of itchy red eruptions all over the body with swelling since 6 months with daily recurrence. Sulphur was prescribed in a single dose in 1M potency, followed by a single dose of 10M potency after a few days. No new episode was observed in the last 1.3 years. There was no need for conventional medicine further. This suggested the positive role of individualized homoeopathic medicines in the treatment of urticaria. Further studies should be warranted to evaluate the role of homoeopathy in urticaria.