DM Medical
Genetics or Doctorate of Medicine in Medical Genetics also known as DM in Medical
Genetics is a super specialty level course for doctors in India that is done by
them after completion of their postgraduate medical degree course. The duration
of this super specialty course is 3 years, and it focuses on the diagnosis, treatment and management of hereditary/genetic disorders.
The course
is a full-time course pursued at various recognized medical colleges across the
country. Some of the top medical colleges offering this course include- Sanjay Gandhi Postgraduate
Institute of Medical Sciences- Lucknow, All India Institute of Medical Sciences-
Rishikesh, Kasturba Medical College- Manipal, and
more.
Admission to this course is done through the NEET-SS Entrance exam
conducted by the National Board of Examinations, followed by counselling based
on the scores of the exam that is conducted by DGHS/MCC/State Authorities.
The fee for pursuing DM (Medical Genetics) varies from college to
college and may range from Rs. 25000 to Rs. 15,00,000 per year.
After completion of their respective course, doctors can either join the
job market or can pursue certificate courses and Fellowship programmes recognised by
NMC and NBE. Candidates can take reputed jobs at positions as Senior residents,
Consultants etc. with an approximate salary range of Rs 5 Lakh- Rs 20 Lakh per year.
What is DM in Medical Genetics?
Doctorate of Medicine in Medical Genetics,
also known as DM (Medical Genetics) or DM in (Medical Genetics) is a three-year super specialty
programme that candidates can pursue after completing postgraduate degree.
Medical Genetics is the branch of medical
science that deals with the diagnosis, treatment and management of hereditary/genetic disorders.
National
Medical Commission (NMC), the apex medical regulator, has released guidelines for a Competency-Based Postgraduate Training Programme for DM in Medical Genetics.
The Competency-Based
Postgraduate Training Programme governs the education and training of DMs in Medical Genetics.
The postgraduate students must gain ample of knowledge and
experience in the diagnosis, treatment of patients with acute, serious, and
life-threatening medical and surgical diseases.
The PG education intends to create specialists who can contribute
to high-quality health care and advances in science through research and
training.
The required training done by a postgraduate specialist in
the field of Medical Genetics would
help the specialist to recognize the health needs of the community. The student
should be competent to handle medical problems effectively and should be aware
of the recent advances in their speciality.
The candidate is also expected to know the principles of
research methodology and modes of the consulting library. The candidate should
regularly attend conferences, workshops and CMEs to upgrade her/ his knowledge.
Course
Highlights
Here are some of the course highlights of DM in Medical Genetics
Name of Course |
DM in Medical Genetics |
Level |
Doctorate |
Duration of Course |
Three years |
Course Mode |
Full Time |
Minimum Academic |
Postgraduate medical degree obtained |
Admission Process / |
Entrance Exam (NEET-SS) INI CET for various Counselling by DGHS/MCC/State |
Course Fees |
Rs. 25000 to Rs. 15,00,000 per year |
Average Salary |
Rs 5 Lakh- Rs 20 Lakh per year |
Eligibility Criteria
The eligibility criteria for DM in Medical Genetics are defined as
the set of rules or minimum prerequisites that aspirants must meet in order to
be eligible for admission, which include:
- Candidates must
be in possession of a postgraduate medical Degree (MD/MS/DNB) from any
college/university recognized by the MCI (Now NMC)/NBE. - The candidate must have obtained permanent
registration of any State Medical Council to be eligible for admission. - The medical college’s recognition cut-off
dates for the Postgraduate Degree courses shall be as prescribed by the Medical
Council of India (now NMC).
Admission Process
- The
admission process contains a few steps to be followed in order by the
candidates for admission to DM in Medical Genetics. Candidates can view the complete admission process for DM in Medical Genetics mentioned
below:
- The
NEET-SS or National Eligibility Entrance Test for Super specialty courses is a
national-level master’s level examination conducted by the NBE for admission to
DM/MCh/DrNB Courses.
- Qualifying Criteria-Candidates
placed at the 50th percentile or above shall be declared as qualified in the
NEET-SS in their respective specialty.
- The following Medical institutions are
not covered under centralized admissions for DM/MCh courses through
NEET-SS:
- AIIMS, New Delhi and other AIIMS
- 2.PGIMER, Chandigarh
- 3.JIPMER, Puducherry
- 4.NIMHANS, Bengaluru
- Candidates from all eligible
feeder specialty subjects shall be required to appear in the question paper of
respective group, if they are willing to opt for a superspecialty course in any
of the super specialty courses covered in that group.
- A candidate can opt for appearing
in the question papers of as many groups for which his/her Postgraduate
specialty qualification is an eligible feeder qualification.
- By appearing in the question
paper of a group and on qualifying the examination, a candidate shall be
eligible to exercise his/her choices in the counseling only for those
superspecialty subjects covered in said group for which his/ her broad
specialty is an eligible feeder qualification.
Fees Structure
The fee structure for DM in Medical Genetics varies from
college to college. The fee is generally less for Government Institutes and
more for private institutes. The average
fee structure for DM in Medical Genetics is around Rs. 25000 to Rs. 15,00,000 per year.
Colleges offering DM in Medical Genetics
There are various medical colleges across India that
offer courses for pursuing DM in (Medical Genetics).
As per National Medical Commission (NMC) website, the
following medical colleges are offering DM in (Medical Genetics)
courses for the academic year 2022-23.
Sl.No. |
Course Name |
Select a State |
Name and Address of |
Annual Intake (Seats) |
1 |
DM – Medical Genetics |
Uttar Pradesh |
Sanjay Gandhi Postgraduate Institute of Medical Sciences, |
2 |
2 |
DM – Medical Genetics |
Uttarakhand |
All India Institute of Medical Sciences, Rishikesh |
4 |
3 |
DM – Medical Genetics |
Karnataka |
Kasturba Medical College, Manipal |
2 |
4 |
DM – Medical Genetics |
Chandigarh |
Postgraduate Institute of Medical Education & Research, |
Syllabus
A DM in Medical Genetics is a three
years specialization course that provides training in the stream of Medical Genetics.
The course content for DM in Medical Genetics is given in the Competency-Based
Postgraduate Training Programme released by National Medical Commission, which
can be assessed through the link mentioned below:
Course
contents:
A. Cognitive
domain
History of
Medical Genetics
Foundations of
Medical Genetics Before 1956
Growth and
Development of Medical Genetics: 1956 to the Present
The Future
Genetics in
Medicine
The Principles
of Disease, Defining Disease, Prevention and Treatment
Nature and
Frequency of Genetic Disease
Frequency of
Genetic Disease
Single-Gene
Disorders
Multifactorial
Disorders
Somatic Cell
Genetic Disorders
Genomics and
Proteomics
Genes and Human
Disease
Genomics
Mapping the
Human Genome
Sequencing the
Human Genome
Current
Approaches to Sequence Human Genome
Cloning Human
Disease Genes
Sequence-Based
Methods for Detecting Chromosomal Abnormalities
Proteomics
Genome and Gene
Structure
Double Helix
Structure, DNA Replication, Transcription, and Meiotic Recombination
Organization of
Genomic DNA
Gene Structure
and the Molecular Pathway of Gene Expression
Epigenetics
Epigenetic
Mechanisms: Chromatin, DNA Methylation and Long Noncoding RNAs
Epigenetic
Reprogramming
Epigenetic
Regulation of X Inactivation
Genomic
Imprinting
Genetic
Disorders Due to Genes Affecting Chromatin Structure
Methods for
Studying Epigenetic Marks
Cancer
Epigenetics
Environmental
Influences on Epigenetic Traits
Abnormalities
in Epigenetic Programming Linked to Infertility and ART
In Utero
Epigenetic Programming of Adult Traits and Disease
Genetic–Epigenetic
Interactions
Human Gene
Mutation in Inherited Disease: Molecular Mechanisms and Clinical Consequences
Molecular
Mechanisms of Mutation Causing Human Inherited Disease
Disease-Causing
Mutations, Consequences of Mutations
General
Principles of Genotype–Phenotype Correlations
Genes in
Families
Pedigree
Construction
Unifactorial
Inheritance/Single-Gene Disorders
Dominance and
Recessiveness
Autosomal-Dominant
Inheritance
Autosomal Recessive
Inheritance
Sex-Linked
Inheritance
X-Linked
Recessive Inheritance
X-Linked
Dominant Inheritance
Y-Linked
(Holandric) Inheritance
Partial Sex
Linkage
Analysis of
Genetic Linkage
Linkage
Analysis: Basic Concepts
Extending
Parametric Linkage Analysis
Linkage
Analysis for Complex and Quantitative Traits
Chromosomal
Basis of Inheritance
Chromosome
Structure, Chromosomes in Cell Division
Methods for
Studying Human Chromosomes
Functional
Organization of Chromosomes
Sex Chromosomes
and Sex Determination
Uniparental
Disomy and Imprinting
Chromosome
Abnormalities
Mitochondrial
Genetics
Mitochondrial
Biology and Genetics
Mitochondrial
Etiology for Diseases and cancer
Therapeutic
Approaches to Mitochondrial Disease
Multifactorial
Inheritance and Complex Diseases
Determining the
Genetic Component of a Trait
The
International HapMap Project
Genome-Wide
Association Studies
Association
Methods/Statistical Analysis
Analysis of
Rare Variants Using New Technologies
Integration of
Genetic, Genomic, and Functional Data for Multifactorial Diseases
Population
Genetics
Hardy–Weinberg
Law, Factors that affect Hardy–Weinberg Equilibrium
Applications in
Population Genetics
Pathogenetics
of Disease
The Scope of
Abnormal Phenotypes: Disease and Malformation
Multivariate
Normal Distributions and the Threshold Model
Pathogenetics
of Refined Traits
Molecular
Pathogenetics
Human
Developmental Genetics
The Concept of
Developmental Fields and Field Defects
Cellular
Signaling in Development
Steps and
Concepts in Embryonic Development
Regulation of
Gene Expression in Development
Organogenesis
Twins and
Twinning
Determining
Zygosity
Incidence of
Twins, Vanishing Twin, Structural Defects in Twins
Twins in
Genetic Studies
Dizygotic
Twins, Monozygotic Twins
The Molecular
Biology of Cancer
Genetic Basis
of Cancer
Viral Oncogenes
Oncogenic
Alleles in Human Cancers
Tumor
Suppressor Genes
The Role of DNA
Damage Repair Genes in Inherited Cancer Syndromes
The Biological
Basis of Aging: Implications for Medical Genetics
Progeroid
Syndromes of Humans
Human Allelic
Variants Homologous to Pro-Longevity Genes
Pharmacogenetics
and Pharmacogenomics
Classical
Genetics and Pharmacogenetics
Ethnic
Differences in Gene–Drug Interactions
Pharmacogenomics
Genetic
Evaluation for Common Diseases of Adulthood
The Process of
Genetic Evaluation for Common Diseases
Integrating
Genetic Information into Routine Clinical Practice
Genetic
Counseling and Clinical Risk Assessment
Process of
Genetic Counseling
Adult-Onset
Disorders
Genetic Risk
Assessment and Calculation in the Clinical Setting
Cytogenetic
Analysis
Milestones in
Human Cytogenetics
The Indications
for Cytogenetic Analysis
Tissue Samples
and Cell Culture, Chromosome Banding
The Normal
Human Karyotype
Chromosome
Abnormalities
In situ
Hybridization
Diagnostic
Molecular Genetics
Indications for
Molecular Genetic Testing
Technical
Approaches to Molecular Genetic Testing
Molecular
Genetic Diagnosis of Diseases
Mitochondrial
DNA Disorders
Quality
Assurance, and Regulatory Issues
Internet
Resources for Molecular Genetic Testing
Heterozygote
Testing and Carrier Screening
Carrier
Screening in Clinical Practice
Carrier
Screening in Individuals of Defined Subpopulation Groups
Therapeutic
Implications for Heterozygotes
Methods and
Tissues used in Carrier Identification
Problems in
Heterozygote Detection
Sensitivity and
Specificity, Cost and Feasibility
Age for Carrier
Testing
Prenatal
Screening for Neural Tube Defects and Aneuploidy
Techniques for
Prenatal Diagnosis
Amniocentesis,
Chorionic Villus Sampling, Fetal Blood Sampling, Fetal Tissue
Sampling,
Celomocentesis
Embryoscopy
Polar Body
Biopsy, Preimplantation Genetic Diagnosis
Ultrasonography
Fetal Cells and
Fetal DNA in Maternal Blood
Neonatal
Screening
Historical
Aspects
Components of
Screening Programs
Potential
Problems in Newborn Screening
Disorders and
Conditions Detected by Newborn Blood Screening
Other Newborn
Screening and Issues and Concerns in Screening
Therapies for
Lysosomal Storage Diseases
ERT for
Lysosomal Storage Diseases
Substrate
Reduction Therapy
Pharmacologic
Chaperone Therapy
Gene Therapy:
From Theoretical Potential to Clinical Implementation
Genes as
Medicines -The Origins of Gene Therapy
The Basic
Science: Gene Transfer
Developing
Cell-Type-Specific and Regulatable Gene Delivery Vectors
The Clinical
Science: Toward Gene Therapy of Human Disease
Ethical and
Social Issues in Clinical Genetics
Genetic
Counseling, Testing and Screening
Goals and
Outcomes of Genetic Services
Non-directiveness
in Genetic Counseling
Diagnostic
Genetic Testing, Predictive Genetic Testing
Confidentiality
Genetic Testing
in Childhood, Population Genetic Screening, Newborn Screening,
Antenatal
Screening, Carrier Screening
Genetics,
Geneticization and Society
Reproductive
Technologies and Cloning: “Reprogenetics”
Legal Issues in
Medical Genetics
Genetic Malpractice
Genetic
Counseling, Abortion, Adoption, Surrogacy, Embryo cryopreservation
Newborn
Screening
Prenatal and
Carrier Screening
Genetic
Discrimination
Regulation of
Genetic Diagnostic Tests
Direct to
Consumer Genetic Testing
Regulation of
Human Genetic Research
Regulation of
Research with Stem Cells Derived from Human Embryos
Genetics of
Male & Female Infertility
The
Hypothalamic – Pituitary – Gonadal Axis
Hypogonadism:
Hypogonadotropic & Hypergonadotropic Hypogonadism
Eugonadal
Infertility
Chromosome
Anomalies and Gene defects
Fetal Loss
Early Pregnancy
Loss, Late Pregnancy Loss
Evaluation and
Management of Recurrent Abortion
Clinical
Approach to the Dysmorphic Child
Prenatal versus
Postnatal Onset of Developmental Problems
Clinical
Teratology
Recognized
Teratogenic Exposures
Paternal
Exposures and Maternal Exposures
Neurodevelopmental
Disabilities: Global Developmental Delay, Intellectual Disability, and
Autism
Abnormal Body
Size and Proportion
Pathologic
Short Stature
Pathologic
Overgrowth
Susceptibility
and Response to Infection
Genome-Wide
Association Studies and Human Infection
Cell Surface
Proteins, Intracellular Proteins, Extracellular Proteins
Transplantation
Genetics
The Physiologic
Function of MHC Molecules
The Structure
of Human Histocompatibility Molecules
Minor
Histocompatibility Systems
Serologic,
Cellular and Molecular Methods for HLA Typing
Clinical
Significance of HLA Molecular Typing
Genetics of
Xenotransplantation
Stem Cells and
Transplantation
The Genetics of
Disorders Affecting the Premature Newborn
Respiratory
Distress Syndrome, Bronchopulmonary Dysplasia
Patent Ductus
Arteriosus
Intraventricular
Hemorrhage
Retinopathy of
Prematurity
Necrotizing
Enterocolitis
Disorders of
DNA Repair and Metabolism
Disorders of
Nucleotide Excision Repair: Xeroderma Pigmentosum and Cockayne
Syndrome
Disorders of
Base Excision Repair: MUTYH and Colon Cancer Risk
Disorders of
Mismatch Repair: Lynch Syndrome and Turcot Syndrome
Disorders
Associated with Double Strand Break Recognition and Repair:
AtaxiaTelangiectasia and Related Conditions
Crosslink
Repair and Homologous Recombination Defects: Breast–Ovarian Cancer and
Fanconi Anemia
Disorders
Associated with Recq Helicase Deficiency: Bloom, Werner, and Rothmund–
Thomson
Syndromes
Gene –
Environment Interactions: Gorlin – Goltz Syndrome
Autosomal
Abnormalities
Genetic
Counseling in the Trisomies
Down Syndrome
(Trisomy 21), Trisomy 18, Trisomy 13
Translocations
Uniparental
Disomy
Deletion,
Duplication
Sex-Chromosome
Abnormalities
Turner
Syndrome, Klinefelter Syndrome, 47,XXX Syndrome, 47,XYY Karyotype
Sex Chromosome
Mosaicism
Sex Chromosome
Tetrasomy and Pentasomy (Polysomy)
Structural
Abnormalities of the Y Chromosome
Prenatal
Diagnosis of Sex Chromosome Abnormalities
Cardio-vascular
system: Congenital Heart Defects and Inherited Cardiomyopathies
Specific
Syndromes with Congenital Heart Defect
Chromosomal
Disorders
Microdeletions/Microduplication
Syndromes
Single-Gene
Disorders
Holt–Oram
syndrome
CHARGE Syndrome
Maternal
Diabetes, Drug Ingestion
Folic Acid
Supplementation
Risks for Sibs
and Offspring of Children with Isolated Heart Defects
Hypertrophic,
Dilated and Atypical Cardiomyopathy
Hereditary
Hemorrhagic Telangiectasia (Osler–Weber–Rendu Syndrome)
Hereditary
Disorders of the Lymphatic System and Venous System (varicose vein)
Capillary
Malformation/Arteriovenous Malformation (Capillary Malformation, Sturge–
Weber Syndrome,
Capillary Malformation–arteriovenous Malformation, Cerebral
Cavernous
Malformation)
The Genetics of
Cardiac Electrophysiology in Humans
Genetics of
Blood Pressure Regulation
Preeclampsia
Common Genetic
Determinants of Coagulation and Fibrinolysis (Genetic Variants
Influencing
Components of the Coagulation Cascade, Genetic Variants Influencing
Natural
Anticoagulants, Genetic Variants Influencing Components of the Fibrinolytic
Cascade,
Genetic Variants Influencing Platelet Function, Genome-Wide Association
Analysis for
Thrombosis)
Genetics of
Atherosclerotic Cardiovascular Disease (Genetic Studies of CHD, Candidate
Gene Studies in
Humans, Genome Wide Association Studies, GWAS Findings for CVD
Risk Factors,
Genetic Risk Scores and Prediction Algorithms for Personalized Medicine)
Respiratory
tract disorders
Cystic Fibrosis
Genetic
Underpinnings of Asthma and Related Traits
Disorders of
ciliary function
Hereditary
Pulmonary Emphysema
Interstitial and
Restrictive Pulmonary Disorders
Congenital
Anomalies of the Kidney and Urinary Tract
Cystic Diseases
of the Kidney
Nephrotic
Disorders
Renal Tubular
Disorders
Cancer of the
Kidney and Urogenital Tract
Gastrointestinal
Tract and Hepatobiliary Duct System
Inflammatory
Bowel Disease
Bile Pigment
Metabolism and its Disorders including cholestasis
Cancer of the
Colon and Gastrointestinal Tract
Blood
Hemoglobinopathies
and Thalassemia
Other
Hereditary Red Blood Cell Disorders
Hemophilia and
Other Disorders of Hemostasis
Rhesus and
Other Fetomaternal Incompatibilities
Disorders of
bone marrow aplasia and dyserythropoesis
Immunologic
Disorders: Autoimmunity: Genetics and Immunologic Mechanisms
Immunodeficiency
Disorders
Inherited
Complement Deficiencies
Disorders of
Leukocyte Function
Genetic Basis
of Autoimmune Thyroid Disease
Endocrine
Abnormalities
of growth hormone- pituitary axis
Monogenic
diabetes mellitus
Susceptibility
to type I and type II diabetes
Genetic Basis
of Thyroid Carcinoma
Familial
Hypocalciuric Hypercalcemia
CASR Mutations
in Familial Hypocalciuric Hypercalcemia and Neonatal Severe
Hyperparathyroidism
Neonatal
Hyperparathyroidism
Multiple
Endocrine Neoplasia
Familial
Isolated Hypoparathyroidism
NHERF1
Mutations and Renal Responsiveness to Parathyroid Hormone
Adrenal Gland
Congenital
Adrenal Hyperplasia (21, 11β, 3β, 17α-Hydroxylase Deficiency, 17,20-Lyase
Deficiency,
Congenital Lipoid Adrenal Hyperplasia, etc): Prenatal Diagnosis and
Treatment
Congenital
adrenal hypoplasia
Reproductive
system
Disorders of
the Gonads, Genital Tract, and Genitalia
Disorders of
Sexual Development and differentiation
Hereditary
Cancers
Familial Breast
Cancers (BRCA1, BRCA2)
Familial Breast
or Ovarian Cancer
Familial
Ovarian Cancer
Familial
Endometrial Cancer
Hereditary
Nonpolyposis Colorectal Cancer Syndrome (or Lynch Syndrome)
Li Fraumeni
syndrome
IEM Amino Acid
Metabolism
Disorders of
Phenylalanine Metabolism
Disorders of
Tyrosine Metabolism
Disorders of
Glycine Metabolism
Disorders of
Proline and Hydroxyproline
Disorders of
the Urea Cycle and Ornithine
Disorders of
Serine Metabolism
IEM Disorders
of Carbohydrate Metabolism
Disorders of
Galactose Metabolism
Disorders of
Fructose Metabolism
Disorders of
Pentose Metabolism
Glycogen
Storage Diseases
Gluconeogenic
Disorders Associated with Lactic Acidosis
Congenital
Disorders of Protein Glycosylation
Congenital
Disorders of Protein N-Glycosylation
Congenital
Disorders of Protein O-Glycosylation
Congenital
Disorders of Protein N- and O-Glycosylation
Purine and
Pyrimidine Metabolism
Lipoprotein and
Lipid Metabolism
Monogenic
Disorders of Lipoprotein Metabolism
Disorders with
Primarily Elevated LDL Cholesterol
Disorders with
Primarily Depressed LDL Cholesterol
Disorders with
Primarily Elevated HDL Cholesterol
Disorders with
Primarily Depressed HDL Cholesterol
Disorders with
Primarily Elevated Triglycerides
Disorders with
Multiple Lipoprotein Disturbances
Organic
Acidemias and Disorders of Fatty Acid Oxidation
Organic
Acidemias
Vitamin D
Metabolism or Action
Hereditary
Vitamin D Dependency Type 1 (VDDR-1)-1-α-Hydroxylase Deficiency
Hereditary
Vitamin D-Dependent Rickets Type 2 (VDDR-2)
States
Resembling Hereditary Generalized Resistance to 1,25(OH)2D
Inherited
Porphyrias
Regulation of
Heme Biosynthesis
Classification
and Diagnosis of the Porphyrias
Inherited
Disorders of Human Copper Metabolism
Menkes Disease
Wilson Disease
Iron Metabolism
and Related Disorders
Syndromes of
Iron Overload
Other Disorders
Resulting in Derangements of Iron Handling
Mucopolysaccharidoses
Mucopolysaccharidosis
I (IH Hurler, IS Scheie and IH/S Hurler–Scheie Disease)
Mucopolysaccharidosis
II (Hunter Syndrome)
Mucopolysaccharidosis
IIIA (Sanfilippo Syndrome, MPS IIIA)
Mucopolysaccharidosis
IIIB (Sanfilippo Syndrome, MPS IIIB)
Mucopolysaccharidosis
IIIC (Sanfilippo Syndrome, MPS IIIC)
Mucopolysaccharidosis
IIID (Sanfilippo Syndrome, MPS IIID)
Mucopolysaccharidosis
IVA and IVB (Morquio Syndrome, MPS IVA, MPS IVB)
Mucopolysaccharidosis
V (Scheie Syndrome, MPS V)
Mucopolysaccharidosis
VI (Maroteaux–Lamy Syndrome, MPS VI)
Mucopolysaccharidosis
VII (Sly Syndrome, MPS VII)
Mucopolysaccharidosis
VIII
Mucopolysaccharidosis
IX (Natowicz Syndrome, MPS IX)
Oligosaccharidoses:
Disorders Allied to the Oligosaccharidoses
Sphingolipid
Disorders and the Neuronal Ceroid Lipofuscinoses or Batten Disease (Wolman
Disease,
Cholesteryl Ester Storage Disease, and Cerebrotendinous Xanthomatosis)
GM1-Gangliosidosis
(β-Galactosidosis)
GM2-Gangliosidosis
Loss-of-Function
Mutation of GM3-Synthase
Niemann–Pick
Disease
Niemann–Pick
Disease, Types A and B
Niemann–Pick
Disease, Types C and D
Farber’s
Disease
Acid Lipase
Deficiency (Wolman Disease and Cholesteryl Ester Storage Disease)
Gaucher Disease
Galactosylceramide
Lipidosis, Globoid Cell Leukodystrophy, or Krabbe Disease
Metachromatic
Leukodystrophy
Fabry Disease
Neuronal Ceroid
Lipofuscinosis or Batten Disease
Kufs Disease or
Adult NCL
Congenital
NCL/CNCL-CLN10/Cathepsin D or CTSD Deficiency
Peroxisomal
Disorders
Nervous System
(CNS & PNS)
Fragile X
Syndrome and X-linked Intellectual Disability
Dyslexia and
Related Communication Disorders
Attention-Deficit/Hyperactivity
Disorder
Autism Spectrum
Disorders
Genetics of
Alzheimer Disease
Schizophrenia
and Affective Disorders
Addictive
Disorders
Neural Tube
Defects
Genetic
Disorders of Cerebral Cortical Development
Genetic Aspects
of Human Epilepsy
Basal Ganglia
Disorders (Parkinson Disease, Dystonias, Choreic Disorders)
Hereditary
Ataxias (Autosomal-Dominant, Recessive, X-linked ataxias, Intermittent
Ataxias,
Episodic Ataxias, Progressive Ataxias, Mitochondrial Ataxias)
Hereditary
Spastic Paraplegia (Autosomal Dominant, Autosomal Recessive, X-Linked)
Autonomic and
Sensory Disorders (Familial Dysautonomia, Congenital Sensory
Neuropathy with
Anhidrosis)
The
Phakomatoses (The Neurofibromatoses)
Tuberous
sclerosis
Demyelinating
Disorders (Krabbe Disease, Metachromatic & X-Linked
Adrenoleukodystrophy)
Hereditary
Motor and Sensory Neuropathies (Charcot–Marie–Tooth)
Spinal Muscular
Atrophies
Motor Neuron
Disease: Familial Amyotrophic Lateral Sclerosis
Muscles
Muscular
Dystrophies (Dystrophinopathies, Facioscapulohumeral Muscular Dystrophy
Emery–Dreifuss
Muscular Dystrophies and Other Contractural Phenotypes, Limb-Girdle
Muscular
Dystrophies, Myofibrillar Myopathies and Other Distal Phenotypes, Congenital
Muscular
Dystrophies)
Congenital
(Structural) Myopathies
Hereditary
Muscle Channelopathies
Myotonic
Dystrophies
Hereditary and
Autoimmune Myasthenias
Eye
Color Vision
Defects (Molecular Basis of Variation in Normal Color Vision, Genetics of
Red–green Color
Vision in Women, Blue–Yellow (Tritan) Color Vision Defects, etc)
The
Achromatopsias
Optic Atrophy
Glaucoma
Congenital
Defects of the Cornea
Congenital
Cataracts and Genetic Anomalies of the Lens
Hereditary
Retinal and Choroidal Dystrophies: Pigmentary Retinopathies/Retinitis
Pigmentosa,
Leber’s Congenital Amaurosis, The Primary Cone Degenerations
Strabismus
Retinoblastoma
and the RB1 Cancer Syndrome
Anophthalmia,
Microphthalmia, and Uveal Coloboma
Ear: Hereditary
Hearing Impairment
Clefting,
Dental, and Craniofacial Syndromes
Craniosynostosis
Skin and Hair
Abnormalities
of Pigmentation: Disorders of Melanosome Biogenesis/Transport—
Hermansky–Pudlak
Syndrome, Chédiak–Higashi Syndrome, and Griscelli Syndrome;
Disorders of
Melanocyte Survival—Vitiligo
Ichthyosiform
Dermatoses
Epidermolysis
Bullosa
Ectodermal
Dysplasias
Xeroderma
Pigmentosum
Epidermodysplasia
Verruciformis
Porokeratoses
Muir–Torre
Syndrome
Melanoma
Cutaneous
Hamartoneoplastic Disorders: Hereditary Leiomyomatosis and Renal-Cell
Cancer,
Birt–Hogg–Dubé Syndrome
Inherited
Disorders of the Hair: Hypotrichosis, Hypertrichosis
Marfan Syndrome
and Related Disorders
Ehlers–Danlos
Syndrome
Heritable
Diseases Affecting the Elastic Fibers: Cutis Laxa, Pseudoxanthoma Elasticum,
and Related
Disorders
Bone
Osteogenesis
Imperfecta (and Other Disorders of Bone Matrix)
Disorders of
Bone Density, Volume, and Mineralization: Osteopetrosis Group of
Disorders,
Raine Dysplasia, Pyknodysostosis, Dysosteosclerosis, Osteopoikilosis,
Craniotubular
Remodeling Disorders, Hyperphosphatasemia with Osteoectasia, etc
Chondrodysplasias
Abnormalities
of Bone Structure (Dysplasia Epiphysealis Hemimelica, Hereditary
Multiple
Exostoses, Langer–Giedion Syndrome, Enchondromatosis, Maffucci Syndrome,
Metachondromatosis,
Fibrous Dysplasia of Bone, etc)
Dysostoses
Arthrogryposes
(Multiple Congenital Contractures)
Common Skeletal
Deformities
Hereditary
Noninflammatory Arthropathies
Cohesinopathies
Ciliopathies
B. Psychomotor
domain:
The student
should be able to understand, learn and/or perform:
1. Elicit a
comprehensive medical genetic history and construct an appropriate pedigree
2. Carry out a
comprehensive physical examination for major and minor anomalies, with
special
attention to surface anatomy and anthropometric measurements
3. Understand
prenatal diagnostic procedures both invasive (amniocentesis, chorionic
villous
sampling, cordocentesis, etc) and non-invasive (fetal ultrasonography)
4. Perform
fetal autopsy
5. Understand
principle of cytogenetic, biochemical, and molecular laboratory methods
6. Perform
specialized tests through biochemical, cytogenetic, and molecular genetic
laboratories
7. Learn
interpretation of cytogenetic, biochemical, and molecular laboratory reports
8. On the basis
of results, formulate an appropriate diagnosis
9. Effectively
use information systems, including library and electronic resources, in the
evaluation and
management of patients with genetic diseases, including diagnosis of
multiple
congenital anomaly syndromes, and the recognition of teratogenic exposures.
10. Ensure that
the testing is done in an Accredited Lab Only (Authenticity and legal
protection for
the referring clinician). Interpretation of the results is an art and science
and hence
should be included empathetically.
11. Appreciate
the role of biomedical research and develop techniques for critical analysis of
current
scientific developments
12. Able to
coordinate information from multiple sources into a coherent and rational plan
of
management of
genetic disorders
13. Able to
communicate and counsel patients and families who sometimes may be disturbed
and
psychologically upset
14. Understand
human behavior, maturation, and intelligence, in order to facilitate counseling
of varying
individuals
Management of
genetic diseases
The student
should be able to:
1. Provide
patients with access to diagnostic and predictive tests that are appropriate
for the
condition in
their family and advise patients of the benefits, limitations, and risks of
such
tests.
2. Demonstrate
use and correct interpretation of diagnostic procedures and their results
3. Advise
appropriate treatments, including dietary, pharmacological, enzyme-replacement,
transplantation,
and gene therapy.
4. Communicate
genetic information in a manner that is suitable for each particular patient
and family.
Present all available option accurately with consequences explained and non
directively.
5. Tolerate and
encourage reiteration of information because of patient anxiety or
unfamiliarity
with the concepts being presented
6. Apply
appropriate communication techniques for conveying bad news
7. Recognize
patients’ defense mechanisms and be able to determine when it is better to
leave them
intact and when they may need to be breached
8. Cope
emotionally with responses of patients
9. Interpret
their own attitudes toward ethical, social, cultural, religious, and ethnic
issues
and develop an
ability to individualize each patient or family member.
10. Resolve
varying cultural, social, and religious attitudes in relation to issues such as
contraception,
abortion, parenting, and gender roles
11. Utilize
community support services and agencies appropriately
12. Plan and
give an appropriate surveillance/ follow-up monitoring plan for anticipated
complications
and issues
13. Understand
all the associated and anticipated multisystem manifestations in order to refer
for appropriate
multidisciplinary management
14. Participate
in treating genetic diseases where applicable; for e.g., Lysosomal Storage
Diseases
(enzyme replacement, substrate reduction & Pharmacologic Chaperone
Therapy),
hypophosphatemia (burosumab), Multiple Exostoses (palovarotene),
Metaphyseal
Chondrodysplasia Schmid type (carbamazepine), Osteoporosis
Pseudoglioma
(lithium carbonate).
Career Options
After completing a DM in Medical
Genetics, candidates will get employment
opportunities in Government as well as in the Private sector.
In the Government
sector, candidates have various options to choose from which include Registrar,
Senior Resident, Demonstrator, Tutor etc.
While
in the Private sector the options include Resident Doctor, Consultant, Visiting
Consultant (Medical Genetics), Junior
Consultant, Senior Consultant (Medical Genetics), Medical
Genetics Specialist
Courses After DM in Medical Genetics Course
DM in Medical Genetics is a specialisation course which
can be pursued after finishing a Postgraduate medical course. After pursuing
specialisation in DM in Medical
Genetics, a candidate could also
pursue certificate courses and Fellowship programmes recognised by NMC and NBE,
where DM in Medical
Genetics is a feeder
qualification.
Frequently Asked Question (FAQs) –DM in Medical Genetics Course
- Question: What is the
full form of DM?
Answer: The full form of DM is Doctorate of Medicine
- Question: What is a DM in Medical
Genetics?
Answer: DM Medical Genetics or Doctorate of Medicine
in Medical Genetics also known as DM in Medical Genetics is a super specialty level course for doctors in
India that is done by them after completion of their postgraduate medical
degree course.
- Question: What is the
duration of a DM in Medical Genetics?
Answer: DM in Medical Genetics is a
super specialty programme of three years.
- Question: What
is the eligibility of a DM in Medical
Genetics?
Answer: Candidates must be in possession of a postgraduate
medical Degree (MD/MS/DNB) from any college/university recognized by the
Medical Council of India (now NMC)/NBE.
- Question: What
is the scope of a DM in Medical Genetics?
Answer: DM in Medical Genetics offers
candidates various employment opportunities and career prospects.
- Question: What
is the average salary for a DM in Medical
Genetics candidate?
Answer: The DM in
Medical Genetics candidate’s
average salary is between Rs 5 Lakh- Rs 20 Lakh per year depending on the experience.
- Question: Can you teach after completing DM Course?
Answer: Yes, candidate can teach in a medical
college/hospital after completing DM course.
- Question: What does a medical geneticist do?
Answer: Medical geneticists
specialize in medicine that involves the interaction between genes and health.
They are trained to evaluate, diagnose, manage, treat and counsel
individuals of all ages with hereditary disorders.