Cannabis not made safer by increasing its CBD content

Cannabis nowadays is widely used for
recreational and medicinal drugs. New research from the Institute of
Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has
found no evidence that cannabidiol (CBD) reduces the negative effects of
cannabis.

The research, published in
Neuropsychopharmacology, challenges the commonly held belief that using
cannabis that contains higher levels of cannabidiol protects the user from
psychotic experiences and memory problems, and suggests that this should be
considered by policy makers currently exploring the topic of medicinal and
recreational use.

46 healthy volunteers completed a
randomised and double-blind trial. Over the course of four experiments, each
participant inhaled cannabis vapour containing 10mg of
Delta-9-tetrahydrocannabinol and a differing level of cannabidiol (0mg, 10mg,
20mg, or 30mg). They then completed a series of tasks, questionnaires and
interviews designed to measure the effect on their cognitive abilities,
severity of psychotic symptoms, and how pleasurable the drug was.

In conclusion this study, explored the
effect of altering the cannabidiol: Delta-9-tetrahydrocannabinol ratio in
cannabis. However, they found increasing the dose of cannabidiol did
not significantly change the effects of Delta-9-tetrahydrocannabinol on
cognitive performance, psychotic symptoms or how pleasurable the drug
experience was.

Reference:

Cannabis not made safer by
increasing its CBD content; KING’S COLLEGE LONDON; JOURNAL: Neuropsychopharmacology,
DOI: 10.1038/s41386-022-01478-z.

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